Searchable abstracts of presentations at key conferences in endocrinology

ea0013p250 | Neuroendocrinology and behaviour (including pituitary) | SFEBES2007

Small vessel remodelling and impaired endothelial-dependent dilatation in subcutaneous resistance arteries in patients with acromegaly

Paisley Angela , Izzard Ashley , Heagerty Tony , Cruickshank Kennedy , Trainer Peter

Patients with acromegaly die prematurely from CVD. Hypertension is more prevalent with increased peripheral vascular resistance thought to be due to structural remodelling of resistance vessels.We investigated structural properties and reactivity of small arteries in 20 healthy controls(55±11 years, 10 m) and 43 patients with acromegaly (55±14 years, 29 m), split into active disease (AD, n=17, 56±15 years, 13 m) or remission (CD, <i...